HL7 RDE Message

Used by clinical applications to send an order to the pharmacy and/or dispensing systems. It may be sent as either an order containing a single pharmacy/treatment order for a patient or as an order containing multiple pharmacy/treatment orders for a patient (e.g., 1 mg tablet of Aspirin, 0.5 mg 0.5% Albuterol).

The transmission of orders occurs between the clinical application placing the order (the placer) and the clinical application filling the order (the filler). Typically, the clinician (e.g., physician) is entering orders on the HIS application which acts as the placer application in HL7 parlance. The system to which the order is targeted (e.g., the lab in the case of a complete blood count order) is the filler of the order.

The three RDE messages include Pharmacy encoded order messages:

  • RDE-001 – ORM – Order message (also RDE, RDS, RGV, RAS)
  • RDE-011 – RDE – Pharmacy/treatment encoded order
  • RDE-025 – RDE – Pharmacy/treatment refill authorization request

The segments and groups of segments in the RDE message are as follows, and apply for all trigger events: 

MSH Message header Required
NTE Notes and comments Optional, Repeatable
PatientGroup – Optional
PID Patient identification Required
PID1 Patient demographics Optional
NTE-1 Notes and comments Optional, Repeatable
PatientVisitGroup – Optional
PV1 Patient visit Required
PV2 Patient visit – additional info Optional
InsuranceGroup – Optional and repeatable group
IN1 Insurance Required
IN2 Insurance additional info Optional
IN3 Insurance additional info certification Optional
GT1 Guarantor Optional
AL1 Patient allergy information Optional, Repeatable
PatientGroup – Optional
OrderGroup – Repeatable
ORC Common order segment Required
PrescriptionOrderGroup – Optional
RXO Pharmacy prescription order segment Required
NTE-2 Notes and comments segment Optional, Repeatable
RXR Pharmacy route segment Repeatable
ComponentOrderGroup – OptionalM
RXC Pharmacy component order segment Repeatable
NTE-3 Notes and comments segment Optional, Repeatable
PrescriptionOrderGroup – Optional
RXE Pharmacy encoded order segment Required
RXR-1 Pharmacy route segment Repeatable
RXC-1 Pharmacy component order segment Optional, Repeatable
ObservationGroup – Repeatable
OBX Observation segment Optional
NTE-4 Notes and comments segment Optional
ObservationGroup – Repeatable
CTI Clinical Trial Identification Optional


In HL7 pipe and hat format, the RDE message would look like this:

MSH|^~\&|CPSI_IF_FEED_OUT|Murphy Medical Center|||20091026120921||RDE|20091026120921|P|2.3||


PID||1061418|1061418||PYXIS^TEST^PATIENT 2||19240829|M||W|4130 US HWY








OBX|2|ST|1010.1^Body Weight||190.00|pounds

AL1|||99999998^No Known Drug Allergies



RXE|1^BID&1000,2200,^^200910150932^^0^0^|361906^PROPRANOLOL 40MG TAB

(INDERAL)|40||MG|EACH|HOLD FOR SBP #lg;90 |||1||||||||||||||




Want to learn more about HL7? Enroll in Lyniate Academy’s HL7 training course now! 

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